The antioxidation effects of Cinnamomi Cortex (CC), Cinnamomi Ramulus (CR), Cinnamomi Petiole (CP) on the radical scavenging ability from 1,1´-Diphenyl-2-picrylhydrazyl (DPPH), activities of nitrate reductase (NR), superoxide dismutase (SOD), xanthine oxidase and lipid peroxidase (LPO) in rat liver cells were examined.
In in vitro studies, CR extract had greater DPPH-radical scavenging ability than CC and CP. The NR acitivity in the cells was more increased by the treatments of CC and CR extracts than CP extract. The enzyme activity of Xanthine oxidase of CC was decreased. Also, levels of lipid peroxidation were proportionally decreased to concentrations of CR. The recovery by CR extract treatment was similar to the level of ascorbic acid treatment. Therefore, it seems that CR extract has similar effects on the antioxidation compared with ascorbic acid, well-known antioxidant.
The data indicate that CR has a depressive effect on the production of free radicals and changes in the acitivities of enzymes involved in the antioxidation. Compared to others, CP had smaller effects on the antioxidation.
These results suggest that CR seems to have more potent effects on the antioxidation than other parts of Cinamomum cassia and different mechanisms might be involved in the anitoxidation processes of CC, CP, and CR.
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